Publications
16. “Deoxygenative radical cross-coupling of C(sp3)−O/C(sp3)−H bonds promoted by hydrogen-bond interaction”
Nat. Commun. 2024, 15, 6745. pdf
Yue Wang, Suping Zhang, Ke Zeng, Pengli Zhang, Xiaorong Song, Tie-Gen Chen* and Guoqin Xia*
15. “Ligand-Controlled Enantioselective and Regiodivergent Construction of 1,2- and 1,3-Disubstituted Alicycles”
Org. Lett. 2024, 26, 7938. pdf
Ke Zeng, Ludi Li, Xiaoyao Luo, Yue Wang, Xiaorong Song, Pengli Zhang* and Guoqin Xia*
14. “Nickel-Catalyzed, Enantioselective Hydrofluoromethylation of Olefins: Access to Chiral α Fluoromethylated Amides”
Org. Lett. 2023, 25, 2218. pdf
Yiming Du, Shuxin Chen, Hexiang Cao, Yichen Zhang, Hongtao Lei, Guoqin Xia,* Huicai Huang* and Zhaodong Li*
13. “Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance”
Science 2024, 386, eadk9893. pdf
Madeline R. Luth, Karla P. Godinez-Macias, Daisy Chen, John Okombo, Vandana Thathy, Xiu Cheng, Sindhu Daggupati, Heledd Davies, Satish K. Dhingra, Jan M. Economy, Rebecca C. S. Edgar, Maria G. Gomez-Lorenzo, Eva S. Istvan, Juan Carlos Jado, Gregory M. LaMonte, Bruno Melillo, Sachel Mok, Sunil K. Narwal, Tolla Ndiaye, Sabine Ottilie, Sara Palomo Diaz, Heekuk Park, Stella Peña, Frances Rocamora, Tomoyo Sakata-Kato, Jennifer L. Small-Saunders, Robert L. Summers, Patrick K. Tumwebaze, Manu Vanaerschot, Guoqin Xia, Tomas Yeo, Ashley You, Francisco-Javier Gamo, Daniel E. Goldberg, Marcus C. S. Lee, Case W. McNamara, Daouda Ndiaye, Philip J. Rosenthal, Stuart L. Schreiber, Gloria Serra, Jair Lage De Siqueira-Neto, Tina S. Skinner-Adams, Anne-Catrin Uhlemann, Nobutaka Kato, Amanda K. Lukens, Dyann F. Wirth, David A. Fidock and Elizabeth A. Winzeler*
12. “Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders”
J.Am. Chem. Soc. 2024, 146, 10393. pdf
Zhonglin Liu, Jarrett R. Remsberg, Haoxin Li, Evert Njomen, Kristen E. DeMeester, Yongfeng Tao, Guoqin Xia, Rachel E. Hayward, Minjin Yoo, Tracey Nguyen, Gabriel M. Simon, Stuart L. Schreiber, Bruno Melillo,* and Benjamin F. Cravatt*
11. “Genetic crosses within and between species of Cryptosporidium”
PANS 2024, 121, e2313210120. pdf
Sebastian Shaw, Ian S. Cohn, Rodrigo P. Baptista, Guoqin Xia, Bruno Melillo, Fiifi Agyabeng-Dadzie, Jessica C. Kissinger, and Boris Striepen*
10. “Diversity-oriented synthesis encoded by deoxyoligonucleotides”
Nat. Commun. 2023, 14, 4930. pdf
Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp, Zher Yin Tan, Praveen Kokkonda, Ben I. C. Tresco, Shuang Liu, Andrew G. Reidenbach, Katherine S. Lim, Jennifer Poirier, John Capece, Simone Bonazzi, Christian M. Gampe, Nichola J. Smith, James E. Bradner, Connor W. Coley, Paul A. Clemons, Bruno Melillo, C. Suk-Yee Hon, Johannes Ottl, Christoph E. Dumelin, Jonas V. Schaefer, Ann Marie E. Faust, Frédéric Berst, Stuart L. Schreiber, Frédéric J. Zécri* and Karin Briner
9. “Ligand enabled b-methylene C(sp3)-H arylation of masked aliphatic alcohols.”
Angew. Chem. Int. Ed. 2020, 59, 7783. pdf
Guoqin Xia, Zhe Zhuang, Luo-Yan Liu, Stuart L. Schreiber, Bruno Melillo, Jin-Quan Yu*
8. “δ-C–H mono- and di-halogenation of alcohols”
J. Am. Chem. Soc. 2020, 142, 2766. pdf
Alastair N. Herron, Dongxin Liu, Guoqin Xia and Jin-Quan Yu*
7. “Reversing conventional site-selectivity in C(sp3)-H bond activation.”
Nature Chemistry 2019, 11, 571. pdf
Guoqin Xia, Jiang Weng, Luoyan Liu, Pritha Verma, Ziqi Li and Jin-Quan Yu*
6. “Ligand-accelerated non-directed C‒H functionalization of arenes.”
Nature 2017, 551, 489. pdf
Peng Wang, Pritha Verma, Guoqin Xia, Jun Shi, Jennifer X. Qiao, Shiwei Tao, Peter T. W. Cheng, Michael A. Poss, Marcus E. Farmer, Kap-Sun Yeung and Jin-Quan Yu*
5. “Enantioselective amine α-functionalization via palladium-catalysed C–H arylation of thioamitdes.”
Nature Chemistry 2017, 9, 140. pdf
Pankaj Jain, Pritha Verma, Guoqin Xia and Jin-Quan Yu*
4. “Cationic Pd (II)-Catalyzed Cyclization of N-Tosyl-aniline Tethered Alkynyl Ketones Initiated by Hydropalladation of Alkynes: A Facile Way to 1, 2-Dihydro or 1, 2, 3, 4-Tetrahydroquinoline Derivatives.”
Org. Chem. Front. 2015, 2, 145. pdf
Kun Shen, Xiuling Han,* Guoqin Xia and Xiyan Lu*
3. “Efficient Synthesis of Heterocyle-Fused β-Naphthylamines via Intramolecular Addition to a Cyano Group Initiated by Nucleopalladation of Alkynes.”
Org. Lett. 2014, 16, 6184. pdf
Guoqin Xia, Xiuling Han and Xiyan Lu*
2. “Pd(II)-Catalyzed One-Step Construction of Cycloalkane-Fused Indoles and Its Application in Formal Synthesis of (±)-Aspidospermidine.”
Org. Lett. 2014, 16, 2058. pdf
Guoqin Xia, Xiuling Han and Xiyan Lu*
1. “Palladium(II)-Catalyzed Tandem Cyclization of 2-(Alk-2’-ynyloxy)benzonitriles or 2-(Alk-2’-ynylamino)- benzonitriles: A Facile Way to 2H-Chromene and 1,2-Dihydroquinoline Derivatives.”
Adv. Synth. Catal. 2012, 354, 2701. pdf
Guoqin Xia, Xiuling Han and Xiyan Lu*
